Runar Health · Research-based estimate

PhenoAge Calculator

Estimate your phenotypic age from nine routine blood biomarkers and chronological age. Review the result, understand the age gap, and keep a private local history of repeat calculations.

9 blood markers Levine PhenoAge model Calculated in your browser
Step 01 · Enter values

Your age & biomarkers

Complete all 10 fields using the units shown.

10 inputs
Chronological age
Age in completed yearsRange: 18–120
Lab biomarkers
Blood proteinTypical: 35–50
Kidney markerTypical: 45–110
Blood sugarTypical: 3.9–5.6
Inflammation markerMust be > 0
White-cell proportionTypical: 20–45%
Red-cell sizeTypical: 80–100
Red-cell size variationTypical: 11–14.5%
Enzyme markerTypical: 40–120
White-cell countTypical: 4–11
Check your CRP unit: many lab reports show mg/L. Convert it to mg/dL before entering: divide the mg/L value by 10 (for example, 0.5 mg/L = 0.05 mg/dL).
Step 02 · Your estimate

Your PhenoAge result

Calculated from the values you enter below. Results are estimates, not a diagnosis.

Your result will appear here

Enter your chronological age and nine biomarkers, then select Calculate PhenoAge.

—years
Estimated phenotypic age
Chronological age—
PhenoAge—
Age gap (PhenoAge − age)—
Awaiting result

Calculate to see a guide to your age gap.

Age gap guide—
LowerNear ageHigher

Calculations run in this browser. Saved history stays in this browser on this device unless you clear it.

Quick guide

Reading the age gap

The gap is PhenoAge minus chronological age.

Negative gapEstimated PhenoAge is lower than your chronological age.
Near zeroEstimated PhenoAge is close to your chronological age.
Positive gapEstimated PhenoAge is higher than your chronological age.

Saved history

Results are stored locally in this browser. Saving is optional.

No saved results yet. Calculate a result and select Save result to add it here.

Understand your PhenoAge

Clear context to help you interpret the estimate without overreading a single number.

01 What a lower biological age may reflect

PhenoAge combines chronological age with blood markers linked to inflammation, metabolism, blood-cell characteristics and organ function. A lower estimate can be encouraging, but it does not guarantee health or predict an individual’s lifespan.

Metabolic health
Inflammation balance
Healthy blood markers
Long-term function
Energy and recovery
Cardiovascular health
Strength and mobility
Preventive follow-up

For the most useful picture, interpret your result alongside your medical history, symptoms, other measurements and repeat results—not as a stand-alone health score.

02 Understanding the score and age-gap guide

PhenoAge is a research-derived estimate calculated from nine blood biomarkers and chronological age. Age gap is the estimate minus your chronological age. The labels below are a simple visual guide for this page, not medical risk categories or diagnostic thresholds.

Age gapGuide labelInterpretation
−8 years or lowerMuch lowerEstimate is well below chronological age.
−5 to −7 yearsLowerEstimate is several years below chronological age.
−1 to −4 yearsSomewhat lowerEstimate is below chronological age.
Near 0SimilarEstimate is close to chronological age.
+1 to +5 yearsHigherEstimate is above chronological age; consider context and trends.
+6 years or higherMuch higherEstimate is notably above chronological age; review results with a qualified healthcare professional.

Small gaps can shift with normal lab variation and rounding. There is no single age-gap cut-off that establishes whether a person is healthy or unhealthy.

03 Practical habits that support healthy aging

PhenoAge is not a direct measure of your habits. General health practices can support many of the systems represented by its biomarkers, though individual responses vary and not every marker is directly controllable.

Sleep consistencyKeep a regular sleep and wake schedule and protect adequate sleep time.
Strength and cardioBuild a sustainable routine that combines resistance work and aerobic activity.
Balanced nutritionPrioritize varied, minimally processed foods and adequate protein and fiber.
Daily movementWalk regularly, break up long sitting periods and choose activity you can sustain.
Stress and connectionUse supportive routines, relaxation and meaningful social connection.
Follow-up labsDiscuss unexpected results and testing intervals with your healthcare professional.
04 PhenoAge vs. DNA and wearable-based measures

Different aging measures capture different biological or behavioral signals. Their numbers are not interchangeable, and none independently provides a complete measure of health.

DNA methylation clocksEpigenetic patterns

Use DNA methylation data from a biological sample. Different clocks are trained for different outcomes and can vary in cost and interpretation.

PhenoAgeBlood biomarkers

Uses routine clinical blood markers and chronological age to estimate phenotypic age using a published research model.

Wearable measuresDaily trends

Track behavior and signals such as activity, resting heart rate and HRV. These measures do not calculate the same score as PhenoAge.

05 Frequently asked questions
What exactly is biological age?

It is an estimate intended to describe aspects of physiological aging. Different algorithms use different inputs, so biological-age estimates from separate tools may not match.

How accurate is this calculator?

The PhenoAge model was developed and evaluated in population research, but an individual result is not a precise prediction of future health or lifespan. Lab variation, acute illness, medications and unit-entry errors can affect interpretation.

Can I lower my PhenoAge?

Some inputs can change over time, but the score is not a treatment target and a change does not automatically mean health has improved. Focus on overall health and discuss abnormal blood results with a qualified professional.

Does stress affect biological age?

Stress can affect health and behavior, and some blood markers can be influenced by illness and other short-term factors. This calculator cannot identify the cause of an individual result.

How often should I test?

There is no universal interval. Follow your healthcare professional’s advice and, when comparing results, consider using comparable testing conditions and units.

What is a good result?

There is no universal PhenoAge score that defines good health. Trends and the wider clinical picture are more informative than a single estimate.

About the algorithm: This calculator applies the published Levine et al. (2018) PhenoAge model. Linear predictor: xb = −19.9067 − 0.0336×albumin + 0.0095×creatinine + 0.1953×glucose + 0.0954×ln(CRP) − 0.0120×lymphocyte% + 0.0268×MCV + 0.3306×RDW + 0.00188×ALP + 0.0554×WBC + 0.0804×age. Units used here: albumin g/L, creatinine µmol/L, glucose mmol/L, CRP mg/dL, lymphocytes %, MCV fL, RDW %, ALP U/L, WBC 10³/µL and age in years. Formula: Levine ME et al., Aging (2018).

Educational use only. This tool provides an estimate from values entered by you; it is not medical advice, diagnosis or a substitute for care. Reference ranges are illustrative and vary by laboratory, age and clinical context. Review lab results and health concerns with a qualified healthcare professional. © 2026 Runar Health LLC.