Purpose / Benefits
Safety / Notes
Purpose / Benefits
Safety / Notes
Supplement Reference Guide
5 Evidence Labels · 9 Health Systems · 135 Supplement Entries · Search, filter, and review by purpose
5 Evidence Labels
9 Health Systems
Search & Review
Evidence & safety audit Evidence labels reflect confidence for specific outcomes—not popularity, ingredient essentiality alone, or a guarantee of benefit. RDA/AI values describe total daily intake from food and supplements; non-nutrient amounts are illustrative, not prescribed doses. Check formulation, total intake, medicine interactions and independent quality testing. NIH ODS fact sheets · NCCIH herb & supplement guidance · FDA supplement safety
RDA / AI values are population intake references—not supplement-dose recommendations. For other compounds, amounts are illustrative examples only; formulation, indication and safety vary.
| SUPPLEMENT / COMPOUND | Health Category | Select | Potential Role | RDA / AI or Example Amount | Evidence Status |
|---|---|---|---|---|---|
| Vitamin A [1] Vitamin | Inflammation & Immunity | Vision and normal immune function | Adult RDAMen 900 mcg RAE; women 700 mcg RAE | Essential Nutrient | |
| Vitamin B1 (Thiamine) [2] Vitamin | Nutrient Levels | Energy metabolism and nerve function | Adult RDAMen 1.2 mg; women 1.1 mg | Essential Nutrient | |
| Vitamin B2 (Riboflavin) [3] Vitamin | Nutrient Levels | Enzyme cofactor for energy metabolism | Adult RDAMen 1.3 mg; women 1.1 mg | Essential Nutrient | |
| Vitamin B3 (Niacin) [4] Vitamin | Cardiovascular | NAD metabolism; high-dose lipid treatment is clinician-managed | Adult RDAMen 16 mg NE; women 14 mg NE | Essential Nutrient | |
| Vitamin B5 [5] Vitamin | Hormonal Balance | Coenzyme metabolism | Adult AI5 mg | Essential Nutrient | |
| Vitamin B6 (Pyridoxine) [6] Vitamin | Nervous System | Amino-acid metabolism and neurotransmitter synthesis | Adult RDA1.3 mg ages 19–50; age/sex needs can be higher | Essential Nutrient | |
| Biotin (B7) [7] Vitamin | Nutrient Levels | Enzyme cofactor; hair/nail benefits without deficiency are unproven | Adult AI30 mcg | Essential Nutrient | |
| Folate (B9) [8] Vitamin | Nervous System | DNA synthesis and red-blood-cell formation | Adult RDA400 mcg DFE; needs differ in pregnancy | Essential Nutrient | |
| Vitamin B12 [9] Vitamin | Nutrient Levels | Nerve function and red-blood-cell formation | Adult RDA2.4 mcg | Essential Nutrient | |
| Vitamin C [10] Vitamin | Inflammation & Immunity | Collagen synthesis and antioxidant function | Adult RDAMen 90 mg; women 75 mg | Essential Nutrient | |
| Vitamin D3 [11] Vitamin | Inflammation & Immunity | Calcium absorption and bone health | Adult RDA15 mcg (600 IU) ages 19–70; 20 mcg (800 IU) over 70 | Essential Nutrient | |
| Vitamin K2 (MK-7) [12] Vitamin | Body Comp & Strength | Vitamin K roles in clotting and bone proteins; K2-specific outcome claims remain uncertain | Vitamin K AIMen 120 mcg; women 90 mcg; not K2-specific | Essential Nutrient | |
| Calcium [13] Mineral | Body Comp & Strength | Bone structure and neuromuscular function | Adult RDA1,000 mg most adults; 1,200 mg for some older adults | Essential Nutrient | |
| Magnesium [14] Mineral | Nervous System | Nerve, muscle, and electrolyte function | Adult RDAMen 400–420 mg; women 310–320 mg | Essential Nutrient | |
| Zinc [15] Mineral | Hormonal Balance | Enzyme activity and normal immune function | Adult RDAMen 11 mg; women 8 mg | Essential Nutrient | |
| Iron [16] Mineral | Nutrient Levels | Hemoglobin production; supplementation is guided by need/deficiency | Adult RDA8 mg for men and adults over 50; 18 mg for women ages 19–50 | Essential Nutrient | |
| Copper [17] Mineral | Cardiovascular | Iron metabolism and connective-tissue enzymes | Adult RDA900 mcg | Essential Nutrient | |
| Selenium [18] Mineral | Hormonal Balance | Selenoproteins and thyroid enzyme function | Adult RDA55 mcg | Essential Nutrient | |
| Chromium [19] Mineral | Glucose-related pathways; routine supplementation benefit is not established | No RDA / AINo established routine supplement target | Mixed / Conditional | ||
| Iodine [20] Mineral | Hormonal Balance | Thyroid hormone synthesis | Adult RDA150 mcg | Essential Nutrient | |
| Manganese [21] Mineral | Body Comp & Strength | Enzyme cofactor; high intake can be harmful | Adult AIMen 2.3 mg; women 1.8 mg | Essential Nutrient | |
| Boron [22] Mineral | Hormonal Balance | Potential biological roles are under study; no established human requirement | No RDA / AINo established human requirement or standard dose | Limited / Emerging Evidence | |
| Molybdenum [23] Mineral | Nutrient Levels | Molybdenum-dependent enzymes | Adult RDA45 mcg | Essential Nutrient | |
| Potassium [24] Mineral | Cardiovascular | Electrolyte balance and blood pressure; supplements require caution | Adult AIMen 3,400 mg; women 2,600 mg | Essential Nutrient | |
| CoQ10 [25] Antioxidant | Cardiovascular | Mitochondrial enzyme function; clinical benefits depend on indication | Example amount*~100-200 mg | Mixed / Conditional | |
| Omega-3 (Fish Oil) [26] Fatty Acid | Cardiovascular | Provides EPA/DHA; effects vary by product, dose, and clinical goal | Use-specific noteCheck EPA + DHA content; total fish-oil weight is not equivalent | Mixed / Conditional | |
| Omega-3 (ALA) [27] Fatty Acid | Cardiovascular | Essential plant-derived omega-3 fatty acid | ALA adult AIWomen 1.1 g; men 1.6 g | Essential Nutrient | |
| Krill Oil [28] Fatty Acid | Cardiovascular | EPA/DHA source; superiority over fish oil is not established | Example amount*~500-1000 mg | Mixed / Conditional | |
| Cod Liver Oil [29] Fatty Acid | Inflammation & Immunity | EPA/DHA plus variable amounts of vitamins A and D | Use-specific noteProduct-dependent; check vitamin A and D per serving | Mixed / Conditional | |
| GLA [30] Fatty Acid | Body Comp & Strength | Fatty acid studied for skin and inflammatory conditions; results vary | Example amount*~240-320 mg | Mixed / Conditional | |
| CLA [31] Fatty Acid | Small/inconsistent body-composition effects; not an established weight-loss treatment | Use-specific noteNo validated weight-loss dose | Mixed / Conditional | ||
| Phosphatidylcholine [32] Lipid | Nervous System | Choline-containing membrane lipid; added benefits beyond adequacy are uncertain | Example amount*~420-1200 mg | Mixed / Conditional | |
| Citicoline (CDP-Choline) [33] Nootropic | Nervous System | Choline source studied for cognition; broad benefit is not established | Example amount*~250-500 mg | Limited / Emerging Evidence | |
| Betaine (TMG) [34] Amino Acid | Cardiovascular | Can affect homocysteine; clinical-outcome benefits remain uncertain | Example amount*~500-2000 mg | Mixed / Conditional | |
| L-Carnitine (ALCAR) [35] Amino Acid | Nervous System | Mitochondrial transport/metabolism; benefits vary by population | Example amount*~500-2000 mg | Mixed / Conditional | |
| L-Glutamine [36] Amino Acid | Amino acid with clinical uses in selected contexts; general gut claims are not established | Example amount*~5000-10000 mg | Mixed / Conditional | ||
| BCAAs [37] Amino Acid | Body Comp & Strength | Branched-chain amino acids; added benefit is often limited when protein intake is adequate | Example amount*~5000-10000 mg | Mixed / Conditional | |
| Beta-Alanine [38] Amino Acid | May improve repeated high-intensity exercise performance in some protocols | Example amount*~3200-6400 mg | Evidence-Supported · Specific Uses | ||
| L-Arginine [39] Amino Acid | Cardiovascular | Nitric-oxide precursor; performance and cardiovascular results vary | Example amount*~3000-6000 mg | Mixed / Conditional | |
| L-Citrulline [40] Amino Acid | Nitric-oxide precursor studied for exercise; results vary by formulation and outcome | Example amount*~3000-8000 mg | Mixed / Conditional | ||
| L-Tyrosine [41] Amino Acid | Nervous System | Amino-acid precursor studied under acute stress; routine cognitive benefit is uncertain | Example amount*~500-2000 mg | Limited / Emerging Evidence | |
| L-Theanine [42] Amino Acid | Nervous System | Tea amino acid studied for relaxation; clinical evidence is limited | Example amount*~100-400 mg | Limited / Emerging Evidence | |
| Glycine [43] Amino Acid | Nervous System | Amino acid studied for sleep and metabolic outcomes; evidence remains preliminary | Example amount*~3000 mg | Limited / Emerging Evidence | |
| 5-HTP [44] Amino Acid | Nervous System | Serotonin precursor; evidence and interaction risks are use-specific | Example amount*~50-200 mg | Mixed / Conditional | |
| Tryptophan [45] Amino Acid | Nervous System | Essential amino acid obtained from food; added supplementation benefit is context-dependent | Example amount*~500-1000 mg | Mixed / Conditional | |
| Phenylalanine [46] Amino Acid | Nervous System | Amino acid precursor; routine supplementation is not established and PKU is a contraindication | Use-specific noteNo routine supplementation target; avoid with PKU | Insufficient Evidence | |
| NAC [47] Antioxidant | Inflammation & Immunity | Glutathione precursor; supplement evidence varies by indication | Example amount*~600-1200 mg | Mixed / Conditional | |
| Glutathione [48] Antioxidant | Inflammation & Immunity | Antioxidant compound; oral supplement benefits are not established for general wellness | Example amount*~250-500 mg | Limited / Emerging Evidence | |
| Alpha-Lipoic Acid [49] Antioxidant | Antioxidant cofactor studied for neuropathy and metabolic outcomes; findings vary | Example amount*~300-600 mg | Mixed / Conditional | ||
| Resveratrol [50] Polyphenol | Cellular Health | Laboratory longevity pathways; lifespan or healthspan benefit in humans is unproven | Use-specific noteNo established longevity dose | Insufficient Evidence | |
| Curcumin (Turmeric) [51] Polyphenol | Body Comp & Strength | Studied for certain pain/inflammatory symptoms; results depend on formulation and condition | Example amount*~500-1000 mg | Mixed / Conditional | |
| EGCG (Green Tea) [52] Polyphenol | Green-tea catechin; weight effects are small/inconsistent and concentrated extracts carry liver risk | Example amount*~200-400 mg | Mixed / Conditional | ||
| Quercetin [53] Flavonoid | Inflammation & Immunity | Flavonoid studied for allergic/inflammatory pathways; clinical evidence is limited | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Fisetin [54] Flavonoid | Cellular Health | Senolytic hypothesis under study; human longevity benefit is not established | Use-specific noteNo established senolytic dose | Insufficient Evidence | |
| Hesperidin [55] Flavonoid | Cardiovascular | Flavonoid studied for vascular markers; clinical outcome evidence is limited | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Milk Thistle [56] Herb | Liver & Kidneys | Botanical studied for liver-related conditions; reliable clinical benefit is uncertain | Example amount*~200-400 mg | Mixed / Conditional | |
| N-Acetyl Glucosamine [57] Aminosugar | Body Comp & Strength | Aminosugar studied for joint and gut outcomes; evidence is limited | Example amount*~500-1500 mg | Limited / Emerging Evidence | |
| Glucosamine/Chondroitin [58] Aminosugar | Body Comp & Strength | Osteoarthritis symptom evidence is mixed and product-specific | Example amount*~1500-3000 mg | Mixed / Conditional | |
| MSM [59] Organosulfur | Body Comp & Strength | Sulfur-containing compound studied for pain/joint outcomes; evidence is limited | Example amount*~1000-3000 mg | Limited / Emerging Evidence | |
| Collagen Peptides [60] Protein | Body Comp & Strength | Some studies suggest possible modest skin/joint effects; not a general treatment | Example amount*~5000-10000 mg | Mixed / Conditional | |
| Hyaluronic Acid [61] Glycosaminoglycan | Body Comp & Strength | Oral products studied for joint/skin outcomes; evidence is limited | Example amount*~120-240 mg | Limited / Emerging Evidence | |
| Keratin [62] Protein | Body Comp & Strength | Hair/nail structural protein; supplement benefit is not established | Use-specific noteNo validated dose for hair/nail outcomes | Insufficient Evidence | |
| Saw Palmetto [63] Herb | Hormonal Balance | Urinary/prostate symptom studies are mixed; do not assume hormone effects | Example amount*~320 mg | Mixed / Conditional | |
| Beta-Sitosterol [64] Plant Sterol | Cardiovascular | Plant sterol; cholesterol and urinary outcomes depend on dose and indication | Use-specific noteDose and outcome are use-specific; no universal target | Mixed / Conditional | |
| Black Cohosh [65] Herb | Hormonal Balance | Menopause symptom studies are inconsistent; safety requires review | Example amount*~40-80 mg | Mixed / Conditional | |
| Red Clover [66] Herb | Hormonal Balance | Phytoestrogen-containing botanical; clinical benefits are uncertain | Example amount*~40-80 mg | Limited / Emerging Evidence | |
| Dong Quai [67] Herb | Hormonal Balance | Traditional-use botanical; efficacy evidence is limited | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Chasteberry (Vitex) [68] Herb | Hormonal Balance | May help some PMS symptoms in selected studies; preparations vary | Example amount*~20-40 mg | Limited / Emerging Evidence | |
| Fenugreek [69] Herb | Hormonal Balance | Glucose/libido claims vary; human evidence does not support broad guarantees | Example amount*~500-600 mg | Mixed / Conditional | |
| Tribulus [70] Herb | Hormonal Balance | Testosterone-boosting claims are not well supported by clinical evidence | Use-specific noteNo established testosterone-boosting dose | Limited / Emerging Evidence | |
| Maca Root [71] Herb | Hormonal Balance | Small studies examine libido; broader hormone/energy claims remain unproven | Example amount*~1500-3000 mg | Limited / Emerging Evidence | |
| Tongkat Ali [72] Herb | Hormonal Balance | Small preliminary studies; sustained testosterone benefits are not established | Use-specific noteNo established long-term testosterone dose | Limited / Emerging Evidence | |
| Ginkgo Biloba [73] Herb | Nervous System | Cognitive outcomes vary; not established to prevent dementia | Example amount*~120-240 mg | Mixed / Conditional | |
| Panax Ginseng [74] Adaptogen | Studied for fatigue and metabolic outcomes; effects are modest or inconsistent | Example amount*~200-400 mg | Mixed / Conditional | ||
| Rhodiola [75] Adaptogen | Adaptogen studied for fatigue; evidence quality is limited | Example amount*~200-400 mg | Limited / Emerging Evidence | ||
| Ashwagandha [76] Adaptogen | Hormonal Balance | Small trials suggest possible short-term stress/sleep effects; benefits and risks vary | Example amount*~300-600 mg | Mixed / Conditional | |
| Holy Basil [77] Adaptogen | Nervous System | Traditional stress-use botanical; robust clinical evidence is limited | Example amount*~300-600 mg | Limited / Emerging Evidence | |
| Bacopa [78] Nootropic | Nervous System | Small studies report possible memory effects; product and duration matter | Example amount*~300 mg | Limited / Emerging Evidence | |
| Lion’s Mane [79] Fungi | Nervous System | Laboratory nerve-growth findings do not establish human cognitive benefit | Example amount*~500-3000 mg | Limited / Emerging Evidence | |
| Cordyceps [80] Fungi | Performance evidence is inconsistent and extract-specific | Example amount*~1000-3000 mg | Limited / Emerging Evidence | ||
| Reishi [81] Fungi | Nervous System | Laboratory immune mechanisms do not establish clinical immune benefit | Example amount*~1000-3000 mg | Limited / Emerging Evidence | |
| Shiitake / Maitake [82] Fungi | Inflammation & Immunity | Edible mushrooms provide nutrients; supplement-extract outcomes depend on preparation | Example amount*~1000-3000 mg | Limited / Emerging Evidence | |
| Siberian Ginseng [83] Adaptogen | Traditional-use adaptogen; clinical evidence is limited | Example amount*~300-400 mg | Limited / Emerging Evidence | ||
| Schisandra [84] Adaptogen | Liver & Kidneys | Botanical studied for stress/liver outcomes; evidence and safety data are limited | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Licorice (DGL) [85] Herb | Inflammation & Immunity | DGL is distinct from whole licorice; evidence for digestive uses remains limited | Example amount*~380-760 mg | Mixed / Conditional | |
| Ginger [86] Herb | Evidence supports some nausea indications; benefits depend on context and preparation | Example amount*~1000-2000 mg | Evidence-Supported · Specific Uses | ||
| Garcinia Cambogia [87] Herb | Weight-loss evidence is weak and liver-injury reports exist | Use-specific noteNo established effective dose; routine use is not advised | Insufficient Evidence | ||
| Green Coffee Bean [88] Extract | Weight-management studies are small and inconsistent | Example amount*~200-400 mg | Limited / Emerging Evidence | ||
| Yerba Mate [89] Herb | Caffeine-containing botanical; effects depend on caffeine content and preparation | Example amount*~500-1000 mg | Limited / Emerging Evidence | ||
| Kava Kava [90] Herb | Nervous System | Studied for anxiety with mixed evidence; important liver and sedative risks | Use-specific noteNo general-wellness dose; liver risk is a key concern | Mixed / Conditional | |
| Passionflower [91] Herb | Nervous System | Limited evidence for short-term anxiety/sleep; sedation is possible | Example amount*~250-500 mg | Mixed / Conditional | |
| Valerian Root [92] Herb | Nervous System | Insomnia evidence is inconsistent; long-term safety is not well established | Example amount*~300-600 mg | Mixed / Conditional | |
| Hops [93] Herb | Hormonal Balance | Traditional sleep-use botanical; clinical evidence is limited | Example amount*~300-500 mg | Mixed / Conditional | |
| St. John’s Wort [94] Herb | Nervous System | Evidence for some mild-to-moderate depression uses; major medicine interactions limit unsupervised use | Use-specific notePreparation-specific; interaction review is essential | Evidence-Supported · Specific Uses | |
| SAMe [95] Compound | Body Comp & Strength | Studied for mood and osteoarthritis; evidence varies and interactions matter | Example amount*~400-1600 mg | Mixed / Conditional | |
| Methylfolate [96] Vitamin | Nervous System | Active folate form; it is not universally superior to folic acid | Folate referenceFolate RDA is 400 mcg DFE for adults; methylfolate is not universally superior | Mixed / Conditional | |
| NR / NMN [97] NAD Precursor | Cellular Health | Can change NAD-related biomarkers; longevity/clinical benefit is unproven | Use-specific noteNo established longevity dose | Limited / Emerging Evidence | |
| PQQ [98] Compound | Cellular Health | Mitochondrial claims are preliminary; human outcomes are uncertain | Use-specific noteNo established clinical target | Limited / Emerging Evidence | |
| Spermidine [99] Polyamine | Cellular Health | Autophagy/longevity hypothesis; clinical benefits are not established | Use-specific noteNo established longevity dose | Limited / Emerging Evidence | |
| Pomegranate Ext [100] Extract | Cellular Health | Pomegranate polyphenols; conversion to urolithin A varies between people | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Astaxanthin [101] Antioxidant | Cardiovascular | Carotenoid with antioxidant activity; clinical outcome evidence is limited | Example amount*~4-12 mg | Limited / Emerging Evidence | |
| Lutein / Zeaxanthin [102] Carotenoids | Nervous System | Evidence-based AREDS2 formulations apply to specific age-related macular degeneration stages, not general vision enhancement | Example amount*~10-20 mg | Evidence-Supported · Specific Uses | |
| Lycopene [103] Carotenoid | Hormonal Balance | Prostate/cardiovascular associations have not established disease prevention benefit | Example amount*~10-30 mg | Limited / Emerging Evidence | |
| Sulforaphane [104] Compound | Inflammation & Immunity | Pathway activity is studied; disease-prevention claims are not established | Example amount*~10-50 mg | Limited / Emerging Evidence | |
| Berberine [105] Alkaloid | May affect glucose-related markers; evidence, dose, and interactions matter | Example amount*~500-1500 mg | Mixed / Conditional | ||
| Glucomannan [106] Fiber | Soluble fiber may affect satiety; safe administration with adequate fluid is important | Fiber DV28 g/day total dietary fiber—not a supplement dose | Mixed / Conditional | ||
| Psyllium Husk [107] Fiber | Soluble fiber supports bowel regularity and may modestly lower LDL cholesterol | Fiber DV28 g/day total dietary fiber—not a supplement dose | Evidence-Supported · Specific Uses | ||
| Probiotics [108] Microbiome | Inflammation & Immunity | Benefits are strain- and indication-specific; CFU count alone does not guarantee benefit | Example amount*~1-20B CFU | Mixed / Conditional | |
| S. boulardii [109] Yeast | Inflammation & Immunity | Evidence for selected diarrhea indications is strain- and setting-specific | Example amount*~5-10B CFU | Evidence-Supported · Specific Uses | |
| Butyrate [110] Short-Chain Fatty Acid | Butyrate is biologically relevant to colon-cell metabolism; oral supplement outcomes are uncertain | Example amount*~300-1500 mg | Limited / Emerging Evidence | ||
| Colostrum [111] Dairy | Inflammation & Immunity | Adult performance/gut claims have limited evidence | Example amount*~1000-3000 mg | Limited / Emerging Evidence | |
| Lactoferrin [112] Protein | Inflammation & Immunity | Investigated in iron/infection contexts; broad immune claims are not established | Example amount*~100-300 mg | Limited / Emerging Evidence | |
| HMB [113] Metabolite | Body Comp & Strength | May help selected populations; benefit for healthy trained adults is uncertain | Example amount*~3000 mg | Mixed / Conditional | |
| D-Ribose [114] Sugar | Evidence for ATP recovery or general performance benefit is not established | Example amount*~3000-5000 mg | Limited / Emerging Evidence | ||
| Betaine HCl [115] Acid | Not routine digestion support; consider only for a clinician-identified indication | Use-specific noteNo routine dose; not for self-treatment | Insufficient Evidence | ||
| Bromelain [116] Enzyme | Body Comp & Strength | Oral enzyme products have limited evidence for digestion/injury outcomes | Example amount*~200-500 mg | Limited / Emerging Evidence | |
| Nattokinase [117] Enzyme | Cardiovascular | Clot-prevention/treatment claims are unproven; bleeding interactions are important | Use-specific noteNo established safe/effective dose for clot prevention | Insufficient Evidence | |
| Serrapeptase [118] Enzyme | Body Comp & Strength | Clinical benefit is not sufficiently established | Use-specific noteNo established safe/effective dose | Insufficient Evidence | |
| Urolithin A [119] Metabolite | Cellular Health | Small trials report changes in selected measures; long-term clinical outcomes are unknown | Example amount*~250-500 mg | Limited / Emerging Evidence | |
| Apigenin [120] Flavonoid | Nervous System | Mechanistic claims are largely preclinical; human benefit is unclear | Example amount*~25-50 mg | Limited / Emerging Evidence | |
| Theacrine [121] Alkaloid | Stimulant-like effects are studied; long-term safety and benefit data are limited | Example amount*~50-200 mg | Limited / Emerging Evidence | ||
| L-Carnosine [122] Dipeptide | Cellular Health | Anti-glycation/telomere claims are not established clinical outcomes | Example amount*~500-1000 mg | Limited / Emerging Evidence | |
| Vinpocetine [123] Alkaloid | Nervous System | Cognitive benefits are not established; significant safety/regulatory concerns apply | Use-specific noteNo routine supplement dose; safety concerns apply | Insufficient Evidence | |
| Huperzine A [124] Alkaloid | Nervous System | Acetylcholinesterase inhibitor; long-term supplement benefit and safety are uncertain | Example amount*~0.05-0.2 mg | Limited / Emerging Evidence | |
| TUDCA [125] Bile Acid | Liver & Kidneys | Liver “detox” claims are not established for routine supplement use | Use-specific noteNo established general-wellness dose | Insufficient Evidence | |
| Nettle (Root Extract) [126] Herb | Hormonal Balance | Urinary/prostate evidence varies; testosterone claims are unproven | Example amount*~300-600 mg | Mixed / Conditional | |
| Echinacea [127] Herb | Inflammation & Immunity | Cold outcomes vary by species and preparation; results are inconsistent | Example amount*~300-1000 mg | Mixed / Conditional | |
| Astragalus [128] Adaptogen | Inflammation & Immunity | Clinical immune and telomere-protection claims are unproven | Example amount*~500-1500 mg | Limited / Emerging Evidence | |
| Garlic (Aged Extract) [129] Herb | Cardiovascular | Some studies show modest blood-pressure changes; antimicrobial claims are not established for oral supplements | Example amount*~600-1200 mg | Mixed / Conditional | |
| Matcha [130] Tea | Nervous System | Tea provides caffeine and polyphenols; not a proven therapeutic intervention | Example amount*~1000-2000 mg | Mixed / Conditional | |
| Sea Moss [131] Algae | Hormonal Balance | Iodine content can be high and variable; thyroid benefit is not established | Use-specific noteIodine content varies widely; no reliable universal dose | Insufficient Evidence | |
| Moringa [132] Herb | Inflammation & Immunity | Nutrient content varies; clinical anti-inflammatory benefits remain preliminary | Example amount*~1000-3000 mg | Limited / Emerging Evidence | |
| Mullein [133] Herb | Inflammation & Immunity | Traditional respiratory use; robust human efficacy evidence is lacking | Use-specific noteNo validated respiratory-treatment dose | Limited / Emerging Evidence | |
| Artichoke Ext [134] Extract | Liver & Kidneys | Small studies examine dyspepsia/lipids; strong liver-detox/bile-flow claims are unproven | Example amount*~300-600 mg | Mixed / Conditional | |
| Dandelion Root [135] Herb | Liver & Kidneys | Liver-detox and reliable diuretic effects are not established | Use-specific noteNo validated liver-detox dose | Limited / Emerging Evidence |
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