Supplement Optimization – Runar Health
Supplement Optimization – Runar Health
Supplement Optimization – Runar Health
Supplement Reference Guide | Runar Health
Supplement Reference Guide – Runar Health
Supplement Reference Guide | Runar Health

Runar Health
Clinical Reference

Supplement Reference Guide

5 Evidence Labels · 9 Health Systems · 135 Supplement Entries · Search, filter, and review by purpose

5 Evidence Labels 9 Health Systems Search & Review
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Reference only. Supplements are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting new regimens.
Evidence & safety audit Evidence labels reflect confidence for specific outcomes—not popularity, ingredient essentiality alone, or a guarantee of benefit. RDA/AI values describe total daily intake from food and supplements; non-nutrient amounts are illustrative, not prescribed doses. Check formulation, total intake, medicine interactions and independent quality testing. NIH ODS fact sheets · NCCIH herb & supplement guidance · FDA supplement safety
RDA / AI values are population intake references—not supplement-dose recommendations. For other compounds, amounts are illustrative examples only; formulation, indication and safety vary.
SUPPLEMENT / COMPOUNDHealth CategorySelectPotential RoleRDA / AI or Example AmountEvidence Status
Vitamin A [1]
Vitamin
Inflammation & ImmunityVision and normal immune functionAdult RDAMen 900 mcg RAE; women 700 mcg RAEEssential Nutrient
Vitamin B1 (Thiamine) [2]
Vitamin
Nutrient LevelsEnergy metabolism and nerve functionAdult RDAMen 1.2 mg; women 1.1 mgEssential Nutrient
Vitamin B2 (Riboflavin) [3]
Vitamin
Nutrient LevelsEnzyme cofactor for energy metabolismAdult RDAMen 1.3 mg; women 1.1 mgEssential Nutrient
Vitamin B3 (Niacin) [4]
Vitamin
CardiovascularNAD metabolism; high-dose lipid treatment is clinician-managedAdult RDAMen 16 mg NE; women 14 mg NEEssential Nutrient
Vitamin B5 [5]
Vitamin
Hormonal BalanceCoenzyme metabolismAdult AI5 mgEssential Nutrient
Vitamin B6 (Pyridoxine) [6]
Vitamin
Nervous SystemAmino-acid metabolism and neurotransmitter synthesisAdult RDA1.3 mg ages 19–50; age/sex needs can be higherEssential Nutrient
Biotin (B7) [7]
Vitamin
Nutrient LevelsEnzyme cofactor; hair/nail benefits without deficiency are unprovenAdult AI30 mcgEssential Nutrient
Folate (B9) [8]
Vitamin
Nervous SystemDNA synthesis and red-blood-cell formationAdult RDA400 mcg DFE; needs differ in pregnancyEssential Nutrient
Vitamin B12 [9]
Vitamin
Nutrient LevelsNerve function and red-blood-cell formationAdult RDA2.4 mcgEssential Nutrient
Vitamin C [10]
Vitamin
Inflammation & ImmunityCollagen synthesis and antioxidant functionAdult RDAMen 90 mg; women 75 mgEssential Nutrient
Vitamin D3 [11]
Vitamin
Inflammation & ImmunityCalcium absorption and bone healthAdult RDA15 mcg (600 IU) ages 19–70; 20 mcg (800 IU) over 70Essential Nutrient
Vitamin K2 (MK-7) [12]
Vitamin
Body Comp & StrengthVitamin K roles in clotting and bone proteins; K2-specific outcome claims remain uncertainVitamin K AIMen 120 mcg; women 90 mcg; not K2-specificEssential Nutrient
Calcium [13]
Mineral
Body Comp & StrengthBone structure and neuromuscular functionAdult RDA1,000 mg most adults; 1,200 mg for some older adultsEssential Nutrient
Magnesium [14]
Mineral
Nervous SystemNerve, muscle, and electrolyte functionAdult RDAMen 400–420 mg; women 310–320 mgEssential Nutrient
Zinc [15]
Mineral
Hormonal BalanceEnzyme activity and normal immune functionAdult RDAMen 11 mg; women 8 mgEssential Nutrient
Iron [16]
Mineral
Nutrient LevelsHemoglobin production; supplementation is guided by need/deficiencyAdult RDA8 mg for men and adults over 50; 18 mg for women ages 19–50Essential Nutrient
Copper [17]
Mineral
CardiovascularIron metabolism and connective-tissue enzymesAdult RDA900 mcgEssential Nutrient
Selenium [18]
Mineral
Hormonal BalanceSelenoproteins and thyroid enzyme functionAdult RDA55 mcgEssential Nutrient
Chromium [19]
Mineral
Metabolic HealthGlucose-related pathways; routine supplementation benefit is not establishedNo RDA / AINo established routine supplement targetMixed / Conditional
Iodine [20]
Mineral
Hormonal BalanceThyroid hormone synthesisAdult RDA150 mcgEssential Nutrient
Manganese [21]
Mineral
Body Comp & StrengthEnzyme cofactor; high intake can be harmfulAdult AIMen 2.3 mg; women 1.8 mgEssential Nutrient
Boron [22]
Mineral
Hormonal BalancePotential biological roles are under study; no established human requirementNo RDA / AINo established human requirement or standard doseLimited / Emerging Evidence
Molybdenum [23]
Mineral
Nutrient LevelsMolybdenum-dependent enzymesAdult RDA45 mcgEssential Nutrient
Potassium [24]
Mineral
CardiovascularElectrolyte balance and blood pressure; supplements require cautionAdult AIMen 3,400 mg; women 2,600 mgEssential Nutrient
CoQ10 [25]
Antioxidant
CardiovascularMitochondrial enzyme function; clinical benefits depend on indicationExample amount*~100-200 mgMixed / Conditional
Omega-3 (Fish Oil) [26]
Fatty Acid
CardiovascularProvides EPA/DHA; effects vary by product, dose, and clinical goalUse-specific noteCheck EPA + DHA content; total fish-oil weight is not equivalentMixed / Conditional
Omega-3 (ALA) [27]
Fatty Acid
CardiovascularEssential plant-derived omega-3 fatty acidALA adult AIWomen 1.1 g; men 1.6 gEssential Nutrient
Krill Oil [28]
Fatty Acid
CardiovascularEPA/DHA source; superiority over fish oil is not establishedExample amount*~500-1000 mgMixed / Conditional
Cod Liver Oil [29]
Fatty Acid
Inflammation & ImmunityEPA/DHA plus variable amounts of vitamins A and DUse-specific noteProduct-dependent; check vitamin A and D per servingMixed / Conditional
GLA [30]
Fatty Acid
Body Comp & StrengthFatty acid studied for skin and inflammatory conditions; results varyExample amount*~240-320 mgMixed / Conditional
CLA [31]
Fatty Acid
Metabolic HealthSmall/inconsistent body-composition effects; not an established weight-loss treatmentUse-specific noteNo validated weight-loss doseMixed / Conditional
Phosphatidylcholine [32]
Lipid
Nervous SystemCholine-containing membrane lipid; added benefits beyond adequacy are uncertainExample amount*~420-1200 mgMixed / Conditional
Citicoline (CDP-Choline) [33]
Nootropic
Nervous SystemCholine source studied for cognition; broad benefit is not establishedExample amount*~250-500 mgLimited / Emerging Evidence
Betaine (TMG) [34]
Amino Acid
CardiovascularCan affect homocysteine; clinical-outcome benefits remain uncertainExample amount*~500-2000 mgMixed / Conditional
L-Carnitine (ALCAR) [35]
Amino Acid
Nervous SystemMitochondrial transport/metabolism; benefits vary by populationExample amount*~500-2000 mgMixed / Conditional
L-Glutamine [36]
Amino Acid
Metabolic HealthAmino acid with clinical uses in selected contexts; general gut claims are not establishedExample amount*~5000-10000 mgMixed / Conditional
BCAAs [37]
Amino Acid
Body Comp & StrengthBranched-chain amino acids; added benefit is often limited when protein intake is adequateExample amount*~5000-10000 mgMixed / Conditional
Beta-Alanine [38]
Amino Acid
Metabolic HealthMay improve repeated high-intensity exercise performance in some protocolsExample amount*~3200-6400 mgEvidence-Supported · Specific Uses
L-Arginine [39]
Amino Acid
CardiovascularNitric-oxide precursor; performance and cardiovascular results varyExample amount*~3000-6000 mgMixed / Conditional
L-Citrulline [40]
Amino Acid
Metabolic HealthNitric-oxide precursor studied for exercise; results vary by formulation and outcomeExample amount*~3000-8000 mgMixed / Conditional
L-Tyrosine [41]
Amino Acid
Nervous SystemAmino-acid precursor studied under acute stress; routine cognitive benefit is uncertainExample amount*~500-2000 mgLimited / Emerging Evidence
L-Theanine [42]
Amino Acid
Nervous SystemTea amino acid studied for relaxation; clinical evidence is limitedExample amount*~100-400 mgLimited / Emerging Evidence
Glycine [43]
Amino Acid
Nervous SystemAmino acid studied for sleep and metabolic outcomes; evidence remains preliminaryExample amount*~3000 mgLimited / Emerging Evidence
5-HTP [44]
Amino Acid
Nervous SystemSerotonin precursor; evidence and interaction risks are use-specificExample amount*~50-200 mgMixed / Conditional
Tryptophan [45]
Amino Acid
Nervous SystemEssential amino acid obtained from food; added supplementation benefit is context-dependentExample amount*~500-1000 mgMixed / Conditional
Phenylalanine [46]
Amino Acid
Nervous SystemAmino acid precursor; routine supplementation is not established and PKU is a contraindicationUse-specific noteNo routine supplementation target; avoid with PKUInsufficient Evidence
NAC [47]
Antioxidant
Inflammation & ImmunityGlutathione precursor; supplement evidence varies by indicationExample amount*~600-1200 mgMixed / Conditional
Glutathione [48]
Antioxidant
Inflammation & ImmunityAntioxidant compound; oral supplement benefits are not established for general wellnessExample amount*~250-500 mgLimited / Emerging Evidence
Alpha-Lipoic Acid [49]
Antioxidant
Metabolic HealthAntioxidant cofactor studied for neuropathy and metabolic outcomes; findings varyExample amount*~300-600 mgMixed / Conditional
Resveratrol [50]
Polyphenol
Cellular HealthLaboratory longevity pathways; lifespan or healthspan benefit in humans is unprovenUse-specific noteNo established longevity doseInsufficient Evidence
Curcumin (Turmeric) [51]
Polyphenol
Body Comp & StrengthStudied for certain pain/inflammatory symptoms; results depend on formulation and conditionExample amount*~500-1000 mgMixed / Conditional
EGCG (Green Tea) [52]
Polyphenol
Metabolic HealthGreen-tea catechin; weight effects are small/inconsistent and concentrated extracts carry liver riskExample amount*~200-400 mgMixed / Conditional
Quercetin [53]
Flavonoid
Inflammation & ImmunityFlavonoid studied for allergic/inflammatory pathways; clinical evidence is limitedExample amount*~500-1000 mgLimited / Emerging Evidence
Fisetin [54]
Flavonoid
Cellular HealthSenolytic hypothesis under study; human longevity benefit is not establishedUse-specific noteNo established senolytic doseInsufficient Evidence
Hesperidin [55]
Flavonoid
CardiovascularFlavonoid studied for vascular markers; clinical outcome evidence is limitedExample amount*~500-1000 mgLimited / Emerging Evidence
Milk Thistle [56]
Herb
Liver & KidneysBotanical studied for liver-related conditions; reliable clinical benefit is uncertainExample amount*~200-400 mgMixed / Conditional
N-Acetyl Glucosamine [57]
Aminosugar
Body Comp & StrengthAminosugar studied for joint and gut outcomes; evidence is limitedExample amount*~500-1500 mgLimited / Emerging Evidence
Glucosamine/Chondroitin [58]
Aminosugar
Body Comp & StrengthOsteoarthritis symptom evidence is mixed and product-specificExample amount*~1500-3000 mgMixed / Conditional
MSM [59]
Organosulfur
Body Comp & StrengthSulfur-containing compound studied for pain/joint outcomes; evidence is limitedExample amount*~1000-3000 mgLimited / Emerging Evidence
Collagen Peptides [60]
Protein
Body Comp & StrengthSome studies suggest possible modest skin/joint effects; not a general treatmentExample amount*~5000-10000 mgMixed / Conditional
Hyaluronic Acid [61]
Glycosaminoglycan
Body Comp & StrengthOral products studied for joint/skin outcomes; evidence is limitedExample amount*~120-240 mgLimited / Emerging Evidence
Keratin [62]
Protein
Body Comp & StrengthHair/nail structural protein; supplement benefit is not establishedUse-specific noteNo validated dose for hair/nail outcomesInsufficient Evidence
Saw Palmetto [63]
Herb
Hormonal BalanceUrinary/prostate symptom studies are mixed; do not assume hormone effectsExample amount*~320 mgMixed / Conditional
Beta-Sitosterol [64]
Plant Sterol
CardiovascularPlant sterol; cholesterol and urinary outcomes depend on dose and indicationUse-specific noteDose and outcome are use-specific; no universal targetMixed / Conditional
Black Cohosh [65]
Herb
Hormonal BalanceMenopause symptom studies are inconsistent; safety requires reviewExample amount*~40-80 mgMixed / Conditional
Red Clover [66]
Herb
Hormonal BalancePhytoestrogen-containing botanical; clinical benefits are uncertainExample amount*~40-80 mgLimited / Emerging Evidence
Dong Quai [67]
Herb
Hormonal BalanceTraditional-use botanical; efficacy evidence is limitedExample amount*~500-1000 mgLimited / Emerging Evidence
Chasteberry (Vitex) [68]
Herb
Hormonal BalanceMay help some PMS symptoms in selected studies; preparations varyExample amount*~20-40 mgLimited / Emerging Evidence
Fenugreek [69]
Herb
Hormonal BalanceGlucose/libido claims vary; human evidence does not support broad guaranteesExample amount*~500-600 mgMixed / Conditional
Tribulus [70]
Herb
Hormonal BalanceTestosterone-boosting claims are not well supported by clinical evidenceUse-specific noteNo established testosterone-boosting doseLimited / Emerging Evidence
Maca Root [71]
Herb
Hormonal BalanceSmall studies examine libido; broader hormone/energy claims remain unprovenExample amount*~1500-3000 mgLimited / Emerging Evidence
Tongkat Ali [72]
Herb
Hormonal BalanceSmall preliminary studies; sustained testosterone benefits are not establishedUse-specific noteNo established long-term testosterone doseLimited / Emerging Evidence
Ginkgo Biloba [73]
Herb
Nervous SystemCognitive outcomes vary; not established to prevent dementiaExample amount*~120-240 mgMixed / Conditional
Panax Ginseng [74]
Adaptogen
Metabolic HealthStudied for fatigue and metabolic outcomes; effects are modest or inconsistentExample amount*~200-400 mgMixed / Conditional
Rhodiola [75]
Adaptogen
Metabolic HealthAdaptogen studied for fatigue; evidence quality is limitedExample amount*~200-400 mgLimited / Emerging Evidence
Ashwagandha [76]
Adaptogen
Hormonal BalanceSmall trials suggest possible short-term stress/sleep effects; benefits and risks varyExample amount*~300-600 mgMixed / Conditional
Holy Basil [77]
Adaptogen
Nervous SystemTraditional stress-use botanical; robust clinical evidence is limitedExample amount*~300-600 mgLimited / Emerging Evidence
Bacopa [78]
Nootropic
Nervous SystemSmall studies report possible memory effects; product and duration matterExample amount*~300 mgLimited / Emerging Evidence
Lion’s Mane [79]
Fungi
Nervous SystemLaboratory nerve-growth findings do not establish human cognitive benefitExample amount*~500-3000 mgLimited / Emerging Evidence
Cordyceps [80]
Fungi
Metabolic HealthPerformance evidence is inconsistent and extract-specificExample amount*~1000-3000 mgLimited / Emerging Evidence
Reishi [81]
Fungi
Nervous SystemLaboratory immune mechanisms do not establish clinical immune benefitExample amount*~1000-3000 mgLimited / Emerging Evidence
Shiitake / Maitake [82]
Fungi
Inflammation & ImmunityEdible mushrooms provide nutrients; supplement-extract outcomes depend on preparationExample amount*~1000-3000 mgLimited / Emerging Evidence
Siberian Ginseng [83]
Adaptogen
Metabolic HealthTraditional-use adaptogen; clinical evidence is limitedExample amount*~300-400 mgLimited / Emerging Evidence
Schisandra [84]
Adaptogen
Liver & KidneysBotanical studied for stress/liver outcomes; evidence and safety data are limitedExample amount*~500-1000 mgLimited / Emerging Evidence
Licorice (DGL) [85]
Herb
Inflammation & ImmunityDGL is distinct from whole licorice; evidence for digestive uses remains limitedExample amount*~380-760 mgMixed / Conditional
Ginger [86]
Herb
Metabolic HealthEvidence supports some nausea indications; benefits depend on context and preparationExample amount*~1000-2000 mgEvidence-Supported · Specific Uses
Garcinia Cambogia [87]
Herb
Metabolic HealthWeight-loss evidence is weak and liver-injury reports existUse-specific noteNo established effective dose; routine use is not advisedInsufficient Evidence
Green Coffee Bean [88]
Extract
Metabolic HealthWeight-management studies are small and inconsistentExample amount*~200-400 mgLimited / Emerging Evidence
Yerba Mate [89]
Herb
Metabolic HealthCaffeine-containing botanical; effects depend on caffeine content and preparationExample amount*~500-1000 mgLimited / Emerging Evidence
Kava Kava [90]
Herb
Nervous SystemStudied for anxiety with mixed evidence; important liver and sedative risksUse-specific noteNo general-wellness dose; liver risk is a key concernMixed / Conditional
Passionflower [91]
Herb
Nervous SystemLimited evidence for short-term anxiety/sleep; sedation is possibleExample amount*~250-500 mgMixed / Conditional
Valerian Root [92]
Herb
Nervous SystemInsomnia evidence is inconsistent; long-term safety is not well establishedExample amount*~300-600 mgMixed / Conditional
Hops [93]
Herb
Hormonal BalanceTraditional sleep-use botanical; clinical evidence is limitedExample amount*~300-500 mgMixed / Conditional
St. John’s Wort [94]
Herb
Nervous SystemEvidence for some mild-to-moderate depression uses; major medicine interactions limit unsupervised useUse-specific notePreparation-specific; interaction review is essentialEvidence-Supported · Specific Uses
SAMe [95]
Compound
Body Comp & StrengthStudied for mood and osteoarthritis; evidence varies and interactions matterExample amount*~400-1600 mgMixed / Conditional
Methylfolate [96]
Vitamin
Nervous SystemActive folate form; it is not universally superior to folic acidFolate referenceFolate RDA is 400 mcg DFE for adults; methylfolate is not universally superiorMixed / Conditional
NR / NMN [97]
NAD Precursor
Cellular HealthCan change NAD-related biomarkers; longevity/clinical benefit is unprovenUse-specific noteNo established longevity doseLimited / Emerging Evidence
PQQ [98]
Compound
Cellular HealthMitochondrial claims are preliminary; human outcomes are uncertainUse-specific noteNo established clinical targetLimited / Emerging Evidence
Spermidine [99]
Polyamine
Cellular HealthAutophagy/longevity hypothesis; clinical benefits are not establishedUse-specific noteNo established longevity doseLimited / Emerging Evidence
Pomegranate Ext [100]
Extract
Cellular HealthPomegranate polyphenols; conversion to urolithin A varies between peopleExample amount*~500-1000 mgLimited / Emerging Evidence
Astaxanthin [101]
Antioxidant
CardiovascularCarotenoid with antioxidant activity; clinical outcome evidence is limitedExample amount*~4-12 mgLimited / Emerging Evidence
Lutein / Zeaxanthin [102]
Carotenoids
Nervous SystemEvidence-based AREDS2 formulations apply to specific age-related macular degeneration stages, not general vision enhancementExample amount*~10-20 mgEvidence-Supported · Specific Uses
Lycopene [103]
Carotenoid
Hormonal BalanceProstate/cardiovascular associations have not established disease prevention benefitExample amount*~10-30 mgLimited / Emerging Evidence
Sulforaphane [104]
Compound
Inflammation & ImmunityPathway activity is studied; disease-prevention claims are not establishedExample amount*~10-50 mgLimited / Emerging Evidence
Berberine [105]
Alkaloid
Metabolic HealthMay affect glucose-related markers; evidence, dose, and interactions matterExample amount*~500-1500 mgMixed / Conditional
Glucomannan [106]
Fiber
Metabolic HealthSoluble fiber may affect satiety; safe administration with adequate fluid is importantFiber DV28 g/day total dietary fiber—not a supplement doseMixed / Conditional
Psyllium Husk [107]
Fiber
Metabolic HealthSoluble fiber supports bowel regularity and may modestly lower LDL cholesterolFiber DV28 g/day total dietary fiber—not a supplement doseEvidence-Supported · Specific Uses
Probiotics [108]
Microbiome
Inflammation & ImmunityBenefits are strain- and indication-specific; CFU count alone does not guarantee benefitExample amount*~1-20B CFUMixed / Conditional
S. boulardii [109]
Yeast
Inflammation & ImmunityEvidence for selected diarrhea indications is strain- and setting-specificExample amount*~5-10B CFUEvidence-Supported · Specific Uses
Butyrate [110]
Short-Chain Fatty Acid
Metabolic HealthButyrate is biologically relevant to colon-cell metabolism; oral supplement outcomes are uncertainExample amount*~300-1500 mgLimited / Emerging Evidence
Colostrum [111]
Dairy
Inflammation & ImmunityAdult performance/gut claims have limited evidenceExample amount*~1000-3000 mgLimited / Emerging Evidence
Lactoferrin [112]
Protein
Inflammation & ImmunityInvestigated in iron/infection contexts; broad immune claims are not establishedExample amount*~100-300 mgLimited / Emerging Evidence
HMB [113]
Metabolite
Body Comp & StrengthMay help selected populations; benefit for healthy trained adults is uncertainExample amount*~3000 mgMixed / Conditional
D-Ribose [114]
Sugar
Metabolic HealthEvidence for ATP recovery or general performance benefit is not establishedExample amount*~3000-5000 mgLimited / Emerging Evidence
Betaine HCl [115]
Acid
Metabolic HealthNot routine digestion support; consider only for a clinician-identified indicationUse-specific noteNo routine dose; not for self-treatmentInsufficient Evidence
Bromelain [116]
Enzyme
Body Comp & StrengthOral enzyme products have limited evidence for digestion/injury outcomesExample amount*~200-500 mgLimited / Emerging Evidence
Nattokinase [117]
Enzyme
CardiovascularClot-prevention/treatment claims are unproven; bleeding interactions are importantUse-specific noteNo established safe/effective dose for clot preventionInsufficient Evidence
Serrapeptase [118]
Enzyme
Body Comp & StrengthClinical benefit is not sufficiently establishedUse-specific noteNo established safe/effective doseInsufficient Evidence
Urolithin A [119]
Metabolite
Cellular HealthSmall trials report changes in selected measures; long-term clinical outcomes are unknownExample amount*~250-500 mgLimited / Emerging Evidence
Apigenin [120]
Flavonoid
Nervous SystemMechanistic claims are largely preclinical; human benefit is unclearExample amount*~25-50 mgLimited / Emerging Evidence
Theacrine [121]
Alkaloid
Metabolic HealthStimulant-like effects are studied; long-term safety and benefit data are limitedExample amount*~50-200 mgLimited / Emerging Evidence
L-Carnosine [122]
Dipeptide
Cellular HealthAnti-glycation/telomere claims are not established clinical outcomesExample amount*~500-1000 mgLimited / Emerging Evidence
Vinpocetine [123]
Alkaloid
Nervous SystemCognitive benefits are not established; significant safety/regulatory concerns applyUse-specific noteNo routine supplement dose; safety concerns applyInsufficient Evidence
Huperzine A [124]
Alkaloid
Nervous SystemAcetylcholinesterase inhibitor; long-term supplement benefit and safety are uncertainExample amount*~0.05-0.2 mgLimited / Emerging Evidence
TUDCA [125]
Bile Acid
Liver & KidneysLiver “detox” claims are not established for routine supplement useUse-specific noteNo established general-wellness doseInsufficient Evidence
Nettle (Root Extract) [126]
Herb
Hormonal BalanceUrinary/prostate evidence varies; testosterone claims are unprovenExample amount*~300-600 mgMixed / Conditional
Echinacea [127]
Herb
Inflammation & ImmunityCold outcomes vary by species and preparation; results are inconsistentExample amount*~300-1000 mgMixed / Conditional
Astragalus [128]
Adaptogen
Inflammation & ImmunityClinical immune and telomere-protection claims are unprovenExample amount*~500-1500 mgLimited / Emerging Evidence
Garlic (Aged Extract) [129]
Herb
CardiovascularSome studies show modest blood-pressure changes; antimicrobial claims are not established for oral supplementsExample amount*~600-1200 mgMixed / Conditional
Matcha [130]
Tea
Nervous SystemTea provides caffeine and polyphenols; not a proven therapeutic interventionExample amount*~1000-2000 mgMixed / Conditional
Sea Moss [131]
Algae
Hormonal BalanceIodine content can be high and variable; thyroid benefit is not establishedUse-specific noteIodine content varies widely; no reliable universal doseInsufficient Evidence
Moringa [132]
Herb
Inflammation & ImmunityNutrient content varies; clinical anti-inflammatory benefits remain preliminaryExample amount*~1000-3000 mgLimited / Emerging Evidence
Mullein [133]
Herb
Inflammation & ImmunityTraditional respiratory use; robust human efficacy evidence is lackingUse-specific noteNo validated respiratory-treatment doseLimited / Emerging Evidence
Artichoke Ext [134]
Extract
Liver & KidneysSmall studies examine dyspepsia/lipids; strong liver-detox/bile-flow claims are unprovenExample amount*~300-600 mgMixed / Conditional
Dandelion Root [135]
Herb
Liver & KidneysLiver-detox and reliable diuretic effects are not establishedUse-specific noteNo validated liver-detox doseLimited / Emerging Evidence
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